Human ASTL cDNA Clone Expression Plasmid – Cat# MBS1273515

ASTL cDNA Clone – Astacin-Like Metallo-Endopeptidase (M12 Family) (Human)

Name: ASTL cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1273515
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1273515

MBS1273515 is a cDNA clone targeting ASTL. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ASTL, cDNA Clone

Full Product Name

ASTL cDNA Clone

Product Gene Name

ASTL cdna clone

Sequence

ATGGAGGGTG TAGGGGGTCT CTGGCCTTGG GTGCTGGGTC TGCTCTCCTT GCCAGGTGTG ATCCTAGGAG CGCCCCTGGC CTCCAGCTGC GCAGGAGCCT GTGGTACCAG CTTCCCAGAT GGCCTCACCC CTGAGGGAAC CCAGGCCTCC GGGGACAAGG ACATTCCTGC AATTAACCAA GGGCTCATCC TGGAAGAAAC CCCAGAGAGC AGCTTCCTCA TCGAGGGGGA CATCATCCGG CCGAGTCCCT TCCGACTGCT GTCAGCAACC AGCAACAAAT GGCCCATGGG TGGTAGTGGT GTCGTGGAGG TCCCCTTCCT GCTCTCCAGC AAGTACGATG AGCCCAGCCG CCAGGTCATC CTGGAGGCTC TTGCGGAGTT TGAACGTTCC ACGTGCATCA GGTTTGTCAC CTATCAGGAC CAGAGAGACT TCATTTCCAT CATCCCCATG TATGGGTGCT TCTCGAGTGT GGGGCGCAGT GGAGGGATGC AGGTGGTCTC CCTGGCGCCC ACGTGTCTCC AGAAGGGCCG GGGCATTGTC CTTCATGAGC TCATGCATGT GCTGGGCTTC TGGCACGAGC ACACGCGGGC CGACCGGGAC CGCTATATCC GTGTCAACTG GAACGAGATC CTGCCAGGCT TTGAAATCAA CTTCATCAAG TCTCGGAGCA GCAACATGCT GACGCCCTAT GACTACTCCT CTGTGATGCA CTATGGGAGG CTTGCCTTCA GCCGGCGTGG GCTGCCCACC ATCACACCAC TTTGGGCCCC CAGTGTCCAC ATCGGCCAGC GATGGAACCT GAGTGCCTCG GACATCACCC GGGTCCTCCA ACTCTACGGC TGCAGCCCAA GTGGCCCCAG GCCCCGTGGG AGAGGGTCCC ATGCCCACAG CACTGGTAGG AGCCCCGCTC CGGCCTCCCT ATCTCTGCAG CGGCTTTTGG AGGCACTGTC GGCGGAATCC AGGAGCCCCG ACCCCAGTGG TTCCAGTGCG GGAGGCCAGC CCGTTCCTGC AGGGCCTGGG GAGAGCCCAC ATGGGTGGGA GTCCCCTGCC CTGAAAAAGC TCAGTGCAGA GGCCTCGGCA AGGCAGCCTC AGACCCTGGC TTCCTCCCCA AGATCAAGGC CTGGAGCAGG TGCCCCCGGT GTTGCTCAGG AGCAGTCCTG GCTGGCCGGA GTGTCCACCA AGCCCACAGT CCCATCTTCA GAAGCAGGAA TCCAGCCAGT CCCTGTCCAG GGAAGCCCAG CTCTGCCAGG GGGCTGTGTA CCTAGAAATC ATTTCAAGGG GATGTCCGAA GATTAA

Molecular Weight

45,936 Da

OMIM

608860

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ASTL cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ASTL. It may not necessarily be applicable to this product.

NCBI GI #

76828040

NCBI GeneID

431705

NCBI Accession #

BC107127

UniProt Secondary Accession #

Q3KNT0

UniProt Related Accession #

Q6HA08

NCBI Official Full Name

Homo sapiens astacin-like metallo-endopeptidase (M12 family), mRNA

NCBI Official Synonym Full Names

astacin like metalloendopeptidase

NCBI Official Symbol

ASTL

NCBI Official Synonym Symbols

SAS1B

UniProt Protein Name

Astacin-like metalloendopeptidase

UniProt Synonym Protein Names

Oocyte astacin; Ovastacin

Protein Family

Astacin-like metalloendopeptidase

UniProt Gene Name

ASTL

UniProt Entry Name

ASTL_HUMAN

NCBI Protein Information

astacin-like metalloendopeptidase

UniProt Comments for ASTL

ASTL: Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding. Belongs to the peptidase M12A family.

Protein type: Protease; EC 3.4.-.-

Chromosomal Location of Human Ortholog: 2q11.1

Cellular Component: cytoplasm; plasma membrane

Molecular Function: metalloendopeptidase activity; peptidase activity

Biological Process: cell adhesion; fertilization; proteolysis

Research Articles on ASTL

1. The SAS1B metalloproteinase is proposed as a prototype cancer-oocyte tumor surface neoantigen for development of targeted immunotherapeutics with limited on-target/off tumor effects predicted to be restricted to the population of growing oocytes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with ASTL cdna clone

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>4 publications with ASTL and Kidney Diseases
Inflammation Antibodies	>3 publications with ASTL and Inflammation
Gastrointestinal Diseases Antibodies	>2 publications with ASTL and Gastrointestinal Diseases
Neoplasm Metastasis Antibodies	>2 publications with ASTL and Neoplasm Metastasis
Pain Antibodies	>2 publications with ASTL and Pain
Hyperplasia Antibodies	>2 publications with ASTL and Hyperplasia
Nausea Antibodies	>1 publications with ASTL and Nausea
Vomiting Antibodies	>1 publications with ASTL and Vomiting
Heart Diseases Antibodies	>1 publications with ASTL and Heart Diseases
Hemorrhage Antibodies	>1 publications with ASTL and Hemorrhage