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Docebenone Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5769002

MBS5769002 is an inhibitor targeting Docebenone. Docebenone is a selective and orally active inhibitor of 5-LO. More details

Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Docebenone, Inhibitor
Full Product Name
Docebenone
Product Synonym Names
AA 861
Purity/Purification
98%
Preparation and Storage
Powder: -2 degree C for 3 years
In solvent: -80 degree C for 2 years
Molecular Weight
326.436
SMILES
CC1=C(C)C(=O)C(CCCCC#CCCCC#CCO)=C(C)C1=O
Formula
C21H26O3
CAS Number
80809-81-0
Target
Others
Solubility
(<1mg/mL refers to the product slightly soluble or insoluble)
In_vitro
In monkeys, Docebenone (0.01-10uM) suppresses the release of SRS-A by 55-97% with a dose-dependently manner. The antigen-induced SRS-A release from these fragments is dose-dependently inhibited by 25-93% of Docebenone (0.01-10uM) [4]. Docebenone may protect experimental acute necrotizing pancreatitis in rats [3].

Product Categories/Family for Docebenone, inhibitor

Structure of Docebenone, inhibitor

Docebenone, CAS 80809-81-0
Docebenone Inhibitor – Cat# MBS5769002

Structure of Docebenone, inhibitor

Docebenone, CAS 80809-81-0
Docebenone Inhibitor, Structure – Cat# MBS5769002

Product References and Citations for Docebenone, inhibitor

1 Na YH e al Leukotrien B(4 receptor BLT an BLT ar involve i interleukin- productio i PUMA neutrophil induce b Trichomona vaginalis-derive secretor products Inflam Res 201 Feb 1(2):97-102.
2 Huan JK e al AA-861-induce Ca(2+ mobilizatio i Madi Darb canin kidne cells Toxico App Pharmacol 199 De 1 61(2):202-8.
3 Kiriyam M e al Protectiv effec o AA-86 (5-lipoxygenas inhibitor o experimenta acut necrotizin pancreatiti i rats In Pancreatol 199 Jun 3(3):201-8.
4 Yamamur H e al Effec o AA-861 selectiv 5-lipoxygenas inhibitor o model o allerg i severa species Jp Pharmacol 198 Jul 7(3):261-71.

Other Notes

Small volumes of Docebenone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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