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HSCB Lysate – Tissue Lysate

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8413181

Human HSCB Protein Lysate 20ug is provided as a Lyophilized powder.This is a Recombinant Protein Lysate produced in HEK293T cells. This protein lysate can be reconsituted using SDS Sample Buffer. More details

$390 / 0.02 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HSCB, Lysate
Full Product Name
Human HSCB Protein Lysate
Product Gene Name
Product Synonym Names
HSCB; DNAJC20; HSC20; JAC1
Host
Human
Form/Format
Lyophilized
Preparation and Storage
Store at -20 degree C
Once reconsituted, aliquot and store any remaining material at-20 degree C to avoid repeated freeze-thaw cycles.
Molecular Weight
26.7kDa (231aa) confirmed by MALDI-TOF
OMIM
608142
3D Structure
ModBase 3D Structure for Q8IWL3

Other Notes

Small volumes of HSCB lysate vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HSCB purchase

MBS8413181 is a lysate targeting HSCB. Also known as Human HSCB Protein Lysate. Host: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for HSCB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
iron-sulfur cluster co-chaperone protein HscB, mitochondrial isoform 1
NCBI Official Synonym Full Names
HscB mitochondrial iron-sulfur cluster cochaperone
NCBI Official Symbol
HSCB
NCBI Official Synonym Symbols
JAC1; HSC20; DNAJC20
UniProt Protein Name
Iron-sulfur cluster co-chaperone protein HscB, mitochondrial
UniProt Synonym Protein Names
DnaJ homolog subfamily C member 20; Hsc20
Protein Family
UniProt Gene Name
HSCB
UniProt Synonym Gene Names
DNAJC20; HSC20
UniProt Entry Name
HSC20_HUMAN
NCBI Protein Information
iron-sulfur cluster co-chaperone protein HscB, mitochondrial

NCBI Summary for HSCB

This gene encodes a DnaJ-type co-chaperone and member of the heat shock cognate B (HscB) family of proteins. The encoded protein plays a role in the synthesis of iron-sulfur clusters, protein cofactors that are involved in the redox reactions of mitochondrial electron transport and other processes. Cells in which this gene is knocked down exhibit reduced activity of iron-sulfur cluster-dependent enzymes including succinate dehydrogenase and aconitase. The encoded protein may stimulate the ATPase activity of the mitochondrial stress-70 protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
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UniProt Comments for HSCB

HSCB: Acts as a co-chaperone in iron-sulfur cluster assembly in mitochondria. Belongs to the HscB family.

Protein type: Mitochondrial; Chaperone

Chromosomal Location of Human Ortholog: 22q12.1

Cellular Component: centrosome; mitochondrion; cytoplasm; plasma membrane

Molecular Function: protein binding; chaperone binding; metal ion binding

Biological Process: protein folding; iron-sulfur cluster assembly; protein oligomerization
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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