• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

PRKD2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS247140

PKD2, a PKD type protein kinase, contains a N-terminal hydrophobic domain predicted to be a transmembrane region, two cysteine-rich motifs that form zinc finger-like repeats, a pleckstrin homology domain, and a putative kinase domain containing the… More details

$650 / 0.05 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PRKD2 / PKD2, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human PRKD2 / PKD2
Product Gene Name
anti-PRKD2 antibody
Product Synonym Gene Name
PKD2
Product Synonym Names
Anti-PRKD2 / PKD2 Antibody (Internal) IHC-plus; PRKD2; HSPC187; NPKC-D2; Protein kinase D2; DKFZP586E0820; Human PRKD2; PKD2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Gorilla, Human, Monkey
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human PRKD2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DNM2 (50%).
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
80,143 Da
OMIM
607074
3D Structure
ModBase 3D Structure for Q9BZL6
Target Species
Human
Immunogen Description
Synthetic 18 amino acid peptide from internal region of human PRKD2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Dog (89%); Elephant, Panda (83%).
Immunogen Type
Synthetic peptide
Immunogen
PRKD2 / PKD2 antibody was raised against synthetic 18 amino acid peptide from internal region of human PRKD2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Dog (89%); Elephant, Panda (83%).
Antigen Modification
Internal

Product Categories/Family for anti-PRKD2 antibody

Family: Protein Kinase; Subfamily: PKD
Applications Tested/Suitable for anti-PRKD2 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-PRKD2 antibody
IHC-P (0.5 ug/ml)

Immunohistochemistry (IHC) of anti-PRKD2 antibody

Anti-PRKD2 antibody IHC of human stomach. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 0.5 ug/ml.
Rabbit Anti-PRKD2 Polyclonal Antibody – Cat# MBS247140

Immunohistochemistry (IHC) of anti-PRKD2 antibody

Anti-PRKD2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 0.5 ug/ml.
Rabbit Anti-PRKD2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS247140

Other Notes

Small volumes of anti-PRKD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PRKD2 purchase

MBS247140 is an antibody targeting PRKD2. Also known as Rabbit Polyclonal to Human PRKD2 / PKD2. Reactive in Gibbon, Gorilla, Human, Monkey. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PRKD2. It may not necessarily be applicable to this product.

NCBI GI #
19923468
NCBI GeneID
25865
NCBI Accession #
NP_057541.2
UniProt Primary Accession #
Q9BZL6
UniProt Secondary Accession #
Q8NCK8; Q8TB08; Q9P0T6; Q9Y3X8; M0R2R2
UniProt Related Accession #
Q9BZL6
GenBank Nucleotide #
NM_016457.4
NCBI Official Full Name
serine/threonine-protein kinase D2 isoform A
NCBI Official Synonym Full Names
protein kinase D2
NCBI Official Symbol
PRKD2
NCBI Official Synonym Symbols
PKD2; HSPC187; nPKC-D2
UniProt Protein Name
Serine/threonine-protein kinase D2
UniProt Synonym Protein Names
nPKC-D2
Protein Family
Serine/threonine-protein kinase
UniProt Gene Name
PRKD2
UniProt Synonym Gene Names
PKD2
UniProt Entry Name
KPCD2_HUMAN
NCBI Protein Information
serine/threonine-protein kinase D2

NCBI Summary for PRKD2

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for PRKD2

PRKD2: a calcium-independent, phospholipid-dependent CAMK kinase of the PKD family. Activated by diacylglycerol and phorbol esters. may play a role in carcinoid tumor progression.

Protein type: Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; Motility/polarity/chemotaxis; EC 2.7.11.13; CAMK group; PKD family

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; plasma membrane; nucleus

Molecular Function: protein serine/threonine kinase activity; protein binding; protein kinase C activity; metal ion binding; ATP binding; protein kinase activity

Biological Process: cell death; positive regulation of cell adhesion; protein amino acid autophosphorylation; positive regulation of blood vessel endothelial cell migration; activation of CREB transcription factor; positive regulation of fibroblast growth factor receptor signaling pathway; T cell receptor signaling pathway; protein amino acid phosphorylation; positive regulation of peptidyl-serine phosphorylation; positive regulation of vascular endothelial growth factor receptor signaling pathway; activation of NF-kappaB transcription factor; positive regulation of interleukin-8 production; positive regulation of angiogenesis; peptidyl-serine phosphorylation; positive regulation of T cell receptor signaling pathway; positive regulation of interleukin-2 production; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; positive regulation of endothelial cell proliferation; angiogenesis; cell adhesion; vascular endothelial growth factor receptor signaling pathway
Show more

Research Articles on PRKD2

1. Both PKD2 and GOLPH3 play important roles in the progression of human gliomas by promoting cell proliferation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PRKD2 antibody

 Products by Pathway  Pathway Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram

Diseases associated with anti-PRKD2 antibody

 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >2 publications with PRKD2 and Immune System Diseases
 Skin Diseases Antibodies  >1 publications with PRKD2 and Skin Diseases
 Kidney Diseases Antibodies  >1 publications with PRKD2 and Kidney Diseases
 Diabetes Mellitus Antibodies  >1 publications with PRKD2 and Diabetes Mellitus
 Gastrointestinal Diseases Antibodies  >1 publications with PRKD2 and Gastrointestinal Diseases
 Nervous System Diseases Antibodies  >1 publications with PRKD2 and Nervous System Diseases
 Inflammation Antibodies  >1 publications with PRKD2 and Inflammation
 Leukemia, Lymphocytic, Chronic, B-Cell Antibodies  >1 publications with PRKD2 and Leukemia, Lymphocytic, Chronic, B-Cell

Organs/Tissues associated with anti-PRKD2 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4 publications with PRKD2 and Blood
 Vascular Antibodies  >1 publications with PRKD2 and Vascular
 Bone Antibodies  >1 publications with PRKD2 and Bone
 Bone Marrow Antibodies  >1 publications with PRKD2 and Bone Marrow
 Brain Antibodies  >1 publications with PRKD2 and Brain
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000