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AFAP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8555993

MBS8555993 is an antibody targeting AFAP1. Also known as AFAP1-Y451 Rabbit pAb. Reactive in Human. Host: Rabbit. More details

$380 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AFAP1, Polyclonal Antibody
Full Product Name
AFAP1-Y451 Rabbit pAb
Product Gene Name
Product Synonym Names
Actin filament-associated protein 1; 110 kDa actin filament-associated protein; AFAP-110; AFAP1; AFAP
Clonality
Polyclonal
Isotype
Ig
Clone Number
RB45037
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Affinity Purified
OMIM
608252
3D Structure
ModBase 3D Structure for Q8N556
Immunogen
This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 444-477 amino acids from human.
Cellular Localization
Cytoplasm, Cytoskeleton
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-AFAP1 antibody
Western Blot (WB)
Application Notes for anti-AFAP1 antibody
WB: 1:1000

Other Notes

Small volumes of anti-AFAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AFAP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
GenBank Nucleotide #
NCBI Official Full Name
actin filament-associated protein 1 isoform A
UniProt Protein Name
Actin filament-associated protein 1
UniProt Synonym Protein Names
110 kDa actin filament-associated protein
UniProt Gene Name
AFAP1
UniProt Synonym Gene Names
AFAP; AFAP-110
UniProt Entry Name
AFAP1_HUMAN

UniProt Comments for AFAP1

AFAP: Can cross-link actin filaments into both network and bundle structures. May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 4p16

Cellular Component: focal adhesion; cytoplasm; actin cytoskeleton

Molecular Function: actin binding

Biological Process: regulation of signal transduction; regulation of cytoskeleton organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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