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ATRIP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9508569

MBS9508569 is an antibody targeting ATRIP. Also known as ATRIP (Phospho-Ser224) Antibody. Reactive in Human. Host: Rabbit. More details

$335 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ATRIP, Polyclonal Antibody
Full Product Name
ATRIP (Phospho-Ser224) Antibody
Product Gene Name
Product Synonym Names
ATIP; ATM and Rad3 related interacting protein; ATR-interacting protein
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Rabbit IgG in phosphate buffered saline (Phospho-without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Concentration
1 mg/ml (lot specific)
Specificity
ATRIP (Phospho-Ser224) Antibody detects endogenous levels of ATRIP only when phosphorylated at Ser224.
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Molecular Weight
85 kDa
OMIM
AF451323 mRNA
3D Structure
ModBase 3D Structure for Q8WXE1
Target Modification
Phospho
Modification Sites
H:S224
Immunogen
The antiserum was produced against synthesized phospho-peptide derived from human ATRIP around the phosphorylation site of Ser224.
Applications Tested/Suitable for anti-ATRIP antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-ATRIP antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:10000

ELISA (EIA) of anti-ATRIP antibody

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using ATRIP (Phospho-Ser224) Antibody
Rabbit Anti-ATRIP Polyclonal Antibody – Cat# MBS9508569

Western Blot (WB) of anti-ATRIP antibody

Western blot analysis of lysates from 293 cells treated with UV 15', using ATRIP (Phospho-Ser224) Antibody.
Rabbit Anti-ATRIP Polyclonal Antibody, Western Blot (WB) – Cat# MBS9508569

Other Notes

Small volumes of anti-ATRIP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ATRIP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ATR-interacting protein isoform 3
NCBI Official Synonym Full Names
ATR interacting protein
NCBI Official Symbol
ATRIP
UniProt Protein Name
ATR-interacting protein
UniProt Synonym Protein Names
ATM and Rad3-related-interacting protein
UniProt Gene Name
ATRIP
UniProt Synonym Gene Names
AGS1
NCBI Protein Information
ATR-interacting protein

NCBI Summary for ATRIP

This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
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UniProt Comments for ATRIP

Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-ATRIP antibody

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