YY1 Antibody – Rabbit Polyclonal

Short Description: Our YY1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in ChIP-Seq, Immunohistochemistry, Immunoprecipitation and Western blot; it has been shown to react with Human samples.

Background: YY1 (Yin Yang 1) is a transcription factor that belongs to the GLI-Kruppel class of zinc finger transcription factors and is ubiquitously expressed. YY1 is known to have a fundamental role in normal biologic processes such as embryogenesis, differentiation, replication and cellular proliferation. YY1 exerts its effects on genes involved in these processes via its ability to initiate, activate or repress transcription depending upon the context in which it binds. Since expression and function of YY1 are known to be intimately associated with progression through phases of the cell cycle, the physiologic significance of YY1 activity has been applied to models of tumor biology. It can repress and activate a number of gene promoters and direct histone deacetylases (HDACs) and histone acetyltransferases (HATs).

Small volumes of anti-YY1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS389041 is an antibody targeting YY1. Also known as YY1 antibody (pAb). Reactive in Human. Host: Rabbit.