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ASTN2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6275764

This gene encodes a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mouse. A deletion at this locus has been associated with schizophrenia. Multiple… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ASTN2, Polyclonal Antibody
Full Product Name
ASTN2, NT (ASTN2, KIAA0634, Astrotactin-2) (PE)
Product Gene Name
Product Synonym Names
ASTN2; KIAA0634; Astrotactin-2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
142,544 Da
3D Structure
ModBase 3D Structure for O75129
Immunogen
ASTN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-248 amino acids from the N-terminal region of human ASTN2.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-ASTN2 antibody

Applications Tested/Suitable for anti-ASTN2 antibody
Western Blot (WB), FLISA
Application Notes for anti-ASTN2 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-ASTN2 antibody

ASTN2 Antibody (N-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the ASTN2 antibody detected the ASTN2 protein (arrow).
Rabbit Anti-ASTN2 Polyclonal Antibody – Cat# MBS6275764

Product References and Citations for anti-ASTN2 antibody

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Adkins, D.E., et al. Mol. Psychiatry (2010). In press: Lesch, K.P., et al. J Neural Transm 115(11):1573-1585(2008). Vrijenhoek, T., et al. Am. J. Hum. Genet. 83(4):504-510(2008).

Other Notes

Small volumes of anti-ASTN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ASTN2 purchase

MBS6275764 is an antibody targeting ASTN2. Also known as ASTN2, NT (ASTN2, KIAA0634, Astrotactin-2) (PE). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ASTN2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
astrotactin-2 isoform f
NCBI Official Synonym Full Names
astrotactin 2
NCBI Official Symbol
ASTN2
NCBI Official Synonym Symbols
bA67K19.1
UniProt Protein Name
Astrotactin-2
Protein Family
UniProt Gene Name
ASTN2
UniProt Synonym Gene Names
KIAA0634
NCBI Protein Information
astrotactin-2

UniProt Comments for ASTN2

Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (). Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref. 6).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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